APOC2 and THBD

  • Data Source:
  • BioGRID (two hybrid)

APOC2

THBD

Description apolipoprotein C2 thrombomodulin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Cholesterol, total ( 20686565)
  • HDL cholesterol ( 20686565)
  • HDL cholesterol levels ( 28334899)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193044 20864672 19060906 20686565)
  • LDL cholesterol levels ( 28334899)
  • Lipid metabolism phenotypes ( 22286219)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Low density lipoprotein cholesterol levels ( 28548082)
  • Quantitative traits ( 19197348)
  • Total cholesterol levels ( 28334899 28548082)
  • Triglyceride levels ( 28334899)
  • Triglycerides ( 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • PR interval in Tripanosoma cruzi seropositivity ( 24324551)
  • Venous thromboembolism ( 26888256)
Interacting Genes 26 interacting genes: APOL2 BCL2L2 CRYAB DIABLO GAD2 GSDMA IFI27 LETMD1 LPL MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 TTPA UBQLN1 UBQLN2 31 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC19A3 SLC35C2 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID 344 7056
HPRD ID 07457 01764
Ensembl ID ENSG00000234906 ENSG00000178726
Uniprot IDs A0A024R0T9 P02655 P07204
PDB IDs 1BY6 1I5J 1O8T 1SOH 1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3
Enriched GO Terms of Interacting Partners?
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