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THBD

Description thrombomodulin
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Vacuolar Membrane
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Apicolateral Plasma Membrane
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Calcium Ion Binding
  • Protein Binding
  • Signaling Receptor Activity
Biological Process
  • Female Pregnancy
  • Blood Coagulation
  • Response To X-ray
  • Negative Regulation Of Platelet Activation
  • Negative Regulation Of Blood Coagulation
  • Response To Lipopolysaccharide
  • Leukocyte Migration
  • Response To CAMP
  • Negative Regulation Of Fibrinolysis
Pathways
  • Common Pathway of Fibrin Clot Formation
  • Cell surface interactions at the vascular wall
Drugs
  • Drotrecogin alfa
  • Ibuprofen
  • Dexibuprofen
Diseases
  • Inherited thrombophilia
GWAS
  • Blood protein levels in cardiovascular risk ( 28369058)
  • PR interval in Tripanosoma cruzi seropositivity ( 24324551)
  • Venous thromboembolism ( 26888256)
Interacting Genes 31 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC19A3 SLC35C2 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID 7056
HPRD ID 01764
Ensembl ID ENSG00000178726
Uniprot IDs P07204
PDB IDs 1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025