CLEC4G and AZU1

Data Source:
BioGRID (two hybrid)

		CLEC4G	AZU1
Description		C-type lectin domain family 4 member G	azurocidin 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Extrinsic Component Of Membrane Azurophil Granule Membrane Azurophil Granule Lumen Azurophil Granule Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Polysaccharide Binding Fructose Binding Carbohydrate Derivative Binding Glycosylated Region Protein Binding	Serine-type Endopeptidase Activity Protein Binding Heparin Binding Peptidase Activity Toxic Substance Binding Heparan Sulfate Proteoglycan Binding
	Biological Process	Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of T Cell Proliferation Viral Entry Into Host Cell Regulation Of Immune Response Positive Regulation Of Viral Life Cycle	Microglial Cell Activation Proteolysis Inflammatory Response Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Glial Cell Migration Positive Regulation Of Gene Expression Positive Regulation Of Peptidyl-threonine Phosphorylation Antimicrobial Humoral Response Fractalkine Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Tumor Necrosis Factor Production Calcium-mediated Signaling Using Intracellular Calcium Source Monocyte Activation Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Neutrophil Degranulation Cellular Extravasation Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Protein Kinase Activity Macrophage Chemotaxis Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Induction Of Positive Chemotaxis Defense Response To Virus Cell Chemotaxis Protein Kinase C Signaling Neutrophil-mediated Killing Of Bacterium
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Post bronchodilator FEV1 ( 26634245)	Blood protein levels ( 30072576)
Interacting Genes		26 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 WBP2	2 interacting genes: CLEC4G TTK
Entrez ID		339390	566
HPRD ID		16721	01221
Ensembl ID		ENSG00000182566	ENSG00000172232
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P20160
PDB IDs			1A7S 1AE5 1FY1 1FY3
Enriched GO Terms of Interacting Partners?
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