CLEC4G and EIF6

Data Source:
BioGRID (two hybrid)

		CLEC4G	EIF6
Description		C-type lectin domain family 4 member G	eukaryotic translation initiation factor 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Cytosol Preribosome, Large Subunit Precursor Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Polysaccharide Binding Fructose Binding Carbohydrate Derivative Binding Glycosylated Region Protein Binding	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding
	Biological Process	Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of T Cell Proliferation Viral Entry Into Host Cell Regulation Of Immune Response Positive Regulation Of Viral Life Cycle	Ribosomal Subunit Export From Nucleus Maturation Of 5.8S RRNA Maturation Of LSU-rRNA Regulation Of Glycolytic Process Translational Initiation Response To Insulin Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Mature Ribosome Assembly Regulation Of Fatty Acid Biosynthetic Process Regulation Of Megakaryocyte Differentiation Positive Regulation Of Translation Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Copper
Diseases
GWAS		Blood protein levels ( 28240269) Post bronchodilator FEV1 ( 26634245)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Fish- and plant-related diet ( 32066663) Height ( 18391951) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 WBP2	41 interacting genes: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP CEP126 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FUNDC2 GIT1 HIP1 HPF1 ITGB4 LRIF1 MEOX2 MRPS31 MSRB3 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 PTEN RACK1 RPL6 SEPTIN3 TK1 UPF3B USP33 VAC14 WFS1 XRN2 ZBTB26
Entrez ID		339390	3692
HPRD ID		16721	04221
Ensembl ID		ENSG00000182566	ENSG00000242372
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P56537
PDB IDs			6LQM 6LSR 6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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