AGFG2 and EPS15L1

Data Source:
BioGRID (genetic interference)
HPRD (in vitro)

		AGFG2	EPS15L1
Description		ArfGAP with FG repeats 2	epidermal growth factor receptor pathway substrate 15 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit
	Molecular Function	Molecular_function GTPase Activator Activity Metal Ion Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Biological_process Positive Regulation Of GTPase Activity	Endocytosis Endosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hematocrit ( 27863252) Subcortical volume (MOSTest) ( 32665545)	Basophil count ( 32888494) Body size at age 10 ( 32376654) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494 27863252 21738480) White matter integrity ( 23218918)
Interacting Genes		4 interacting genes: APP EPS15 EPS15L1 ITSN1	15 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 LRRC7 NDC80 SGIP1 STON2 TRAPPC2 TRAPPC2B UBC
Entrez ID		3268	58513
HPRD ID		04932	09445
Ensembl ID		ENSG00000106351	ENSG00000127527
Uniprot IDs		A4D2D6 O95081	A0A024R7G6 Q9UBC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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