CDR2L and ELOA

Data Source:
BioGRID (two hybrid)

		CDR2L	ELOA
Description		cerebellar degeneration related protein 2 like	elongin A
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Space Nucleoplasm Elongin Complex Site Of DNA Damage
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter
Pathways			Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756)
Interacting Genes		61 interacting genes: ANKRD11 BFSP2 C1orf216 C4orf46 C9orf24 CCDC146 CCDC153 CCDC185 CCDC187 CCHCR1 CDR2 COX5B EHHADH ELOA FAIM FAM161A FAM161B FAM86C1P HDAC4 HSF2BP INO80B KRT31 KRTAP13-4 LENG1 MESD OIP5 PPP1R18 PRPF31 PSME3 RASAL3 RASD1 REL RINT1 SCNM1 SH2D4A SPRY1 STX11 TBRG4 TCEANC TCHP TCP10L TFIP11 TSGA10IP UBE2I WASHC1 ZBTB42 ZNF19 ZNF250 ZNF35 ZNF417 ZNF572 ZNF629 ZNF648 ZNF655 ZNF669 ZNF688 ZNF80 ZNF835 ZSCAN22 ZSCAN23 ZSCAN26	56 interacting genes: AXIN2 BACH2 BRCA1 CBY2 CCDC57 CDR2L CEP57L1 CEP70 CNTROB CUL5 ELOB ERCC6 EVI5 FAM9B FCHO1 FXR1 GMCL1 GOLGA6A GRIPAP1 HIVEP1 HOMEZ JAKMIP2 KANK2 KLHL2 KRT40 KRTAP10-3 KXD1 LMNA LZTS1 MCC MDFI MED21 MID1 MID2 NAB2 NACC1 NAF1 NFKBID NINL PER2 PLK4 POLR2A PPFIA1 PRDM6 PRMT5 RABEP1 RAD54B RAP1A REXO1 SIRPA SPECC1L TNIP1 TP53BP2 TRIM37 TRIM54 ZNF792
Entrez ID		30850	6924
HPRD ID		11041	02873
Ensembl ID		ENSG00000109089	ENSG00000011007
Uniprot IDs		A0A024R8R6 Q86X02	Q14241
PDB IDs			4HFX
Enriched GO Terms of Interacting Partners?
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