KCNIP1 and SOD3

Data Source:
BioGRID (two hybrid)

		KCNIP1	SOD3
Description		potassium voltage-gated channel interacting protein 1	superoxide dismutase 3
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Extracellular Region Extracellular Space Nucleus Golgi Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Superoxide Dismutase Activity Copper Ion Binding Protein Binding Heparin Binding
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Response To Hypoxia Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Response To Copper Ion
Pathways		Phase 1 - inactivation of fast Na+ channels	Detoxification of Reactive Oxygen Species Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Blood protein levels ( 30072576 29875488) Major depressive disorder ( 23377640)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	9 interacting genes: ASPH FBLN5 GOLM2 KCNIP1 KCNIP3 SGTA SGTB UBQLN1 UBQLN2
Entrez ID		30820	6649
HPRD ID		06879	01708
Ensembl ID		ENSG00000182132	ENSG00000109610
Uniprot IDs		Q9NZI2	A0A140VJU8 P08294
PDB IDs		1S1E 2I2R 2NZ0	2JLP
Enriched GO Terms of Interacting Partners?
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