KCNIP1 and DAAM2

Data Source:
BioGRID (two hybrid)

		KCNIP1	DAAM2
Description		potassium voltage-gated channel interacting protein 1	dishevelled associated activator of morphogenesis 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Extracellular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Actin Binding
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Wnt Signaling Pathway Dorsal Spinal Cord Development Actin Cytoskeleton Organization Negative Regulation Of Oligodendrocyte Differentiation Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Height ( 31562340) Hypospadias ( 25108383) Intraocular pressure ( 29785010) Pulmonary function ( 20010834) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	14 interacting genes: EHHADH EXOSC5 HGS KCNIP1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 MDFI RBMY1A1 RBMY1F REL TH
Entrez ID		30820	23500
HPRD ID		06879	09434
Ensembl ID		ENSG00000182132	ENSG00000146122
Uniprot IDs		Q9NZI2	A0A0J9YYF7 Q86T65
PDB IDs		1S1E 2I2R 2NZ0
Enriched GO Terms of Interacting Partners?
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