GUCY2D and GUCA1B

Data Source:
HPRD (in vitro)

		GUCY2D	GUCA1B
Description		guanylate cyclase 2D, retinal	guanylate cyclase activator 1B
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nuclear Outer Membrane Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane	Photoreceptor Inner Segment Plasma Membrane Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment
	Molecular Function	Peptide Receptor Activity Guanylate Cyclase Activity Protein Kinase Activity Protein Binding ATP Binding GTP Binding Signaling Receptor Activity Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity
	Biological Process	CGMP Biosynthetic Process Protein Phosphorylation Signal Transduction Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction	Receptor Guanylyl Cyclase Signaling Pathway Cell-cell Signaling Body Fluid Secretion Visual Perception Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Guanylate Cyclase Activity
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)	Retinitis pigmentosa (RP)
GWAS		Refractive error ( 32231278)
Interacting Genes		5 interacting genes: GUCA1A GUCA1B GUCA2B RGS9 S100B	3 interacting genes: GUCY2D GUCY2F OTX2
Entrez ID		3000	2979
HPRD ID		02550	03783
Ensembl ID		ENSG00000132518	ENSG00000112599
Uniprot IDs		Q02846	Q7Z3V9 Q9UMX6
PDB IDs		1AWL
Enriched GO Terms of Interacting Partners?
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