CERS2 and ATP6V0C

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CERS2	ATP6V0C
Description		ceramide synthase 2	ATPase H+ transporting V0 subunit c
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process Negative Regulation Of Axon Regeneration Negative Regulation Of Schwann Cell Migration Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration	Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways		Sphingolipid de novo biosynthesis	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Body mass index ( 26426971) Estimated glomerular filtration rate ( 31152163 31015462) Facial attractiveness (female raters) ( 30946739) Glycated hemoglobin levels ( 28898252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Reticulocyte fraction of red cells ( 27863252) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		12 interacting genes: ASGR1 ASGR2 ATP6V0C DRD2 HSP90AA1 IER3IP1 PEX6 SLC19A2 SLC22A1 SLC39A1 TMBIM6 YIF1A	53 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12
Entrez ID		29956	527
HPRD ID		06080	00162
Ensembl ID		ENSG00000143418	ENSG00000185883
Uniprot IDs		Q96G23	P27449
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?