GYPA and TMBIM6

Data Source:
BioGRID (two hybrid)

		GYPA	TMBIM6
Description		glycophorin A (MNS blood group)	transmembrane BAX inhibitor motif containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Endoribonuclease Inhibitor Activity
	Biological Process	Viral Entry Into Host Cell Leukocyte Migration	Negative Regulation Of Immunoglobulin Production Autophagy Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Protein Binding Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of RNA Splicing Cellular Response To Unfolded Protein Negative Regulation Of Apoptotic Process Negative Regulation Of Endoribonuclease Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Response To L-glutamate Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Lung function (low FEV1 vs high FEV1) ( 26423011) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)	General cognitive ability ( 29844566)
Interacting Genes		24 interacting genes: ANKRD29 CLDN5 CREB3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31	68 interacting genes: ADIPOR2 ATP13A1 BCL2 BCL2L1 CD300LG CD79A CD99L2 CDC7 CERS2 CLDN22 COBLL1 CREB3L1 EBP ENPP4 ERP29 ESAM FAM209A FERD3L FGFBP2 FXYD3 GJA5 GJA8 GJB4 GLP1R GPHB5 GPR151 GPR42 GPX8 GYPA GZMK HERPUD2 HJV HTR2C IER3 JSRP1 KCNA10 KCNC1 LIME1 LRRC59 MANBAL MFSD14B MMGT1 MS4A3 ODF4 OPRM1 PI16 PIANP PVR REEP2 RHBDL2 RNF185 SCN3B SIT1 SLAMF6 SLC12A7 SLC41A3 SLC7A1 SOAT2 STEAP1B SYT9 TEX29 TMEM31 TMUB1 TMX2 TNFRSF17 TREML1 UGT2B11 VTI1A
Entrez ID		2993	7009
HPRD ID		07508	02851
Ensembl ID		ENSG00000170180	ENSG00000139644
Uniprot IDs		A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419	A0A024R0Z5 P55061
PDB IDs		1AFO 1MSR 2KPE 2KPF 5EH4 5EH6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?