GYPA and FFAR2

Data Source:
BioGRID (two hybrid)

		GYPA	FFAR2
Description		glycophorin A (MNS blood group)	free fatty acid receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Projection
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	G Protein-coupled Receptor Activity Protein Binding Lipid Binding
	Biological Process	Viral Entry Into Host Cell Leukocyte Migration	Leukocyte Chemotaxis Involved In Inflammatory Response Mucosal Immune Response Regulation Of Acute Inflammatory Response Positive Regulation Of Cytokine Production Involved In Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus G Protein-coupled Receptor Signaling Pathway Lipid Storage Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-8 Production Glucose Homeostasis Fat Cell Differentiation Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion
Pathways		Cell surface interactions at the vascular wall	G alpha (q) signalling events Free fatty acid receptors
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder (body mass index interaction) ( 24322204) Blood pressure (smoking interaction) ( 25189868) Chronic obstructive pulmonary disease ( 30804561 25101718) Diastolic blood pressure ( 27841878) Femoral neck bone mineral density ( 30172743) Height ( 31562340) Lung function (low FEV1 vs high FEV1) ( 26423011) Malaria ( 31844061) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Severe malaria ( 26416757) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White blood cell count ( 32888494)	Hemoglobin ( 32888494) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		24 interacting genes: ANKRD29 CLDN5 CREB3 ELOVL4 ERGIC3 EVA1A FAM209A FFAR2 GOLT1A GPRC5D GPX8 KEAP1 LAPTM5 PDZK1IP1 SAR1A SGTA SGTB SLC10A6 TLCD4 TMBIM6 TMEM14B TMEM154 TMEM237 TMEM31	110 interacting genes: AGPAT4 AGTRAP ALOX5AP APOD ATP13A1 ATP6V0C BMP10 BNIP3 BTN2A2 C11orf24 C3orf52 C4orf3 CACNG1 CBLIF CCDC167 CD82 CDIPT CFHR5 CGRRF1 CLDN4 CLDND2 CLEC1A CMTM5 CMTM7 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB5R2 DERL1 EDDM3B EMP1 ERG28 FAM20B FAM3C FAXDC2 FCER1G FIS1 FXYD3 FXYD6 FZD7 GALNT15 GJB2 GNAO1 GNAQ GPR37L1 GUCA2A GYPA IFITM3 IGF1R KRT1 KTN1 LAPTM4A LAT LEPROTL1 LHFPL5 LPAR3 MALL MFSD5 MS4A13 NAT8 NIPAL4 NKG7 NRM NSG1 NUCB2 OR10AG1 PEX16 PLP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SACM1L SCGB1D1 SELENOK SLC30A2 SLC35B4 SLC35C2 SLC35E3 SLC38A1 SLC39A9 SLC41A1 SMAGP SMCO4 SMIM1 STRIT1 STX8 SYNDIG1 TEX264 TM4SF4 TMEM11 TMEM120B TMEM144 TMEM147 TMEM203 TMEM239 TMEM262 TMEM60 TMEM86A TMEM97 TNF TSPO2 UNC50 UPK1B YIF1A YIPF2 YIPF6
Entrez ID		2993	2867
HPRD ID		07508	04824
Ensembl ID		ENSG00000170180	ENSG00000126262
Uniprot IDs		A0A0C4DFT7 A0A2R8Y7F9 E9PD10 P02724 Q14419	C6KYL4 O15552
PDB IDs		1AFO 1MSR 2KPE 2KPF 5EH4 5EH6
Enriched GO Terms of Interacting Partners?
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