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NME7 and PIAS2
Data Source:
BioGRID
(two hybrid)
NME7
PIAS2
Description
NME/NM23 family member 7
protein inhibitor of activated STAT 2
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Nucleus
Nucleoplasm
PML Body
Nuclear Speck
Molecular Function
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
Transcription Coregulator Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Biological Process
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Protein Sumoylation
Negative Regulation Of Androgen Receptor Signaling Pathway
Pathways
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
)
D-dimer levels (
21502573
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Left-handedness (
32989287
)
Pulse pressure (
27841878
30578418
)
QT interval (
30679814
)
Systolic blood pressure (
27841878
30578418
)
Venous thromboembolism (
21980494
22672568
)
Fruit consumption (
32066663
)
Interacting Genes
75 interacting genes:
AMOTL2
ARHGAP9
BTBD6
C1orf189
CARD10
CBY2
CCDC136
CCDC33
CCDC88B
CCHCR1
CDC42EP2
CEP72
DDIT4L
DDX1
DISC1
DNAI7
EFHC2
FKBP6
FLOT1
FOSL1
FOSL2
GATAD2B
GLIS2
GOLGA2
GSC2
HAUS8
IKZF1
IKZF3
INCA1
ISY1-RAB43
KRT18
KRT75
LNX1
MAP4K4
MED11
MED30
MEI4
MEOX2
MYOT
NAB2
NEFL
NFKBIL1
NIF3L1
NME4
NT5C2
OFD1
PAX4
PIAS2
PICK1
POU6F2
PROSER3
PSMA1
REL
RUBCN
SHTN1
SNAPIN
SNX32
SYCE1
TCF4
TCHP
TEKT1
TEPSIN
THAP10
TNIP1
TNNI2
TRIM27
TRIM48
TUFT1
YWHAQ
ZBTB48
ZNF23
ZNF263
ZNF343
ZNF526
ZNF620
125 interacting genes:
ACY3
ADA
AKT1
AR
ATF2
C1QA
C5orf24
CBS
CBSL
CCHCR1
CCNDBP1
CDCA8
CGGBP1
CHMP4B
CLDN2
CREB1
CREBBP
CTBP1
DDX39B
DES
DEUP1
DMC1
DNMT3A
EDC3
ELK1
ESR1
ESR2
EXOSC8
FAM118B
FKBP6
FLI1
GFAP
GLUL
GOLGA2
GRHL2
GRM8
GTF2I
GTF2IRD1
HDAC3
HMBOX1
HMG20A
HMG20B
HMGXB4
HNRNPCL1
HNRNPUL1
HOMER1
HOOK1
HUWE1
IKZF1
IMPDH1
JUN
KIFC3
LCE1E
LCE2C
LMNA
LMNB1
MAPK8
MAPKAPK2
MBD1
MITF
MLX
MSX2
MX1
MX2
NAV2
NME7
NR3C1
PAICS
PARK7
PAXIP1
PGR
PHC1
PIAS1
PIAS4
PLAG1
PLAGL1
PML
PRKAB2
PRKRA
PRPH
RFX2
RUFY1
RUNX1T1
SEC23A
SIAH1
SIAH2
SMAD3
SMAD4
SNAI2
SNIP1
SOX5
SPATC1L
SPINDOC
SREBF2
STAT4
SUMO1
SUMO1P1
SUMO2
SUMO3
SYN3
TH
TICAM2
TP53
TRAF2
TRAF3
TRAF5
TRIM23
TRIM27
TRIM50
TRIM55
TRIM63
TSR2
TXLNA
UBASH3B
UBE2I
UBE2L3
UBQLN1
ZBED1
ZBTB16
ZBTB8A
ZC3H10
ZFP42
ZNF319
ZNF451
ZNRD2
Entrez ID
29922
9063
HPRD ID
11394
06944
Ensembl ID
ENSG00000143156
ENSG00000078043
Uniprot IDs
A0A024R8Z7
Q9Y5B8
A0A024RC49
O75928
Q2TA77
PDB IDs
2ASQ
4FO9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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