MRPS18B and BMP10

Data Source:
BioGRID (two hybrid)

		MRPS18B	BMP10
Description		mitochondrial ribosomal protein S18B	bone morphogenetic protein 10
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Cell Junction	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc
	Molecular Function	Structural Constituent Of Ribosome Protein Binding	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding
	Biological Process	Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Kidney Development Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Signaling by BMP Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neuroblastoma (pediatric) ( 32599975) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		20 interacting genes: BMP10 CD81 CLEC1A ERCC6 EWSR1 EXOSC6 IGFBP5 LAT LRP10 MIP RB1 SEC22B SLC35A1 SYS1 TMED8 TMEM120B TMEM128 TNFRSF10C TRARG1 ZFPL1	59 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35C2 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR
Entrez ID		28973	27302
HPRD ID		14781	09788
Ensembl ID		ENSG00000204568	ENSG00000163217
Uniprot IDs		B0S7P4 Q9Y676	O95393
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	6SF1 6SF3
Enriched GO Terms of Interacting Partners?
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