BMP10 and COQ9

Data Source:
BioGRID (two hybrid)

		BMP10	COQ9
Description		bone morphogenetic protein 10	coenzyme Q9
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding	Protein Binding Lipid Binding Protein Homodimerization Activity
	Biological Process	Kidney Development Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process
Pathways		Signaling by BMP Molecules associated with elastic fibres	Ubiquinol biosynthesis
Drugs
Diseases			Coenzyme Q10 deficiency
GWAS
Interacting Genes		59 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35C2 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR	33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2
Entrez ID		27302	57017
HPRD ID		09788	13157
Ensembl ID		ENSG00000163217	ENSG00000088682
Uniprot IDs		O95393	A0A024R6U3 O75208
PDB IDs		6SF1 6SF3	4RHP 6AWL 6DEW
Enriched GO Terms of Interacting Partners?
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