GRK6 and LTB4R

Data Source:
HPRD (in vitro)

		GRK6	LTB4R
Description		G protein-coupled receptor kinase 6	leukotriene B4 receptor
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft
	Molecular Function	G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity	Nucleotide Binding Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway	Muscle Contraction Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		G alpha (s) signalling events	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Morniflumate Leukotriene B4
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Cardiac troponin-I levels ( 31014085) Chronic kidney disease ( 20383146) Extremely high intelligence ( 29520040) Glycine levels ( 30837465) Intelligence (MTAG) ( 29326435) Metabolite levels ( 22916037) Neutrophil percentage of white cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		19 interacting genes: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FBXO7 FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R	4 interacting genes: GNA15 GNAI2 GRK6 YWHAG
Entrez ID		2870	1241
HPRD ID		02925	03320
Ensembl ID		ENSG00000198055	ENSG00000213903
Uniprot IDs		B3KPS5 P43250	Q15722
PDB IDs		2ACX 3NYN 3NYO
Enriched GO Terms of Interacting Partners?
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