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P4HA3 and ACOT8
Data Source:
BioGRID
(two hybrid)
P4HA3
ACOT8
Description
prolyl 4-hydroxylase subunit alpha 3
acyl-CoA thioesterase 8
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Peroxisomal Matrix
Cytosol
Molecular Function
Procollagen-proline 4-dioxygenase Activity
Iron Ion Binding
Protein Binding
Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
L-ascorbic Acid Binding
Acetyl-CoA Hydrolase Activity
Succinyl-CoA Hydrolase Activity
Protein Binding
CoA Hydrolase Activity
Palmitoyl-CoA Hydrolase Activity
Choloyl-CoA Hydrolase Activity
Glutaryl-CoA Hydrolase Activity
Acetoacetyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Hydroxymethylglutaryl-CoA Hydrolase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Long-chain Acyl-CoA Hydrolase Activity
Myristoyl-CoA Hydrolase Activity
Biological Process
Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Protein Targeting To Peroxisome
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Fatty Acid Catabolic Process
Viral Process
Peroxisome Fission
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Alpha-linolenic Acid Metabolic Process
Dicarboxylic Acid Catabolic Process
Negative Regulation Of CD4 Production
Pathways
Collagen biosynthesis and modifying enzymes
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
alpha-linolenic acid (ALA) metabolism
Beta-oxidation of pristanoyl-CoA
Beta-oxidation of very long chain fatty acids
Peroxisomal protein import
Peroxisomal protein import
Drugs
Diseases
GWAS
Hippocampal atrophy (
25625606
)
Interacting Genes
50 interacting genes:
ACOT8
ADRA2C
ANAPC11
ATN1
B9D2
BAG4
BLOC1S2
C1orf112
C1QTNF2
CERCAM
CKMT2
CLPP
CT55
CTAG1A
CTAG1B
CTNNBIP1
DTNBP1
FAM136A
GGA3
GPSM3
HGS
KRTAP19-5
KRTAP6-1
KRTAP8-1
LRP2BP
MAGEA2
MAGEA2B
MAGEC2
MCCD1
MEOX2
MSRA
NDN
NICN1
NUTM1
OIP5
P4HB
PROP1
PSMB4
RBFOX1
RUSC1
SCARA5
SERTAD1
SERTAD3
STMN3
TLE5
TOX2
VPS37C
WDR62
ZBTB7B
ZC3H12A
5 interacting genes:
FBXO7
P4HA3
PEX5
PRDM16
REL
Entrez ID
283208
10005
HPRD ID
16413
06998
Ensembl ID
ENSG00000149380
ENSG00000101473
Uniprot IDs
Q7Z4N8
A0A494C0N6
O14734
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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