GLRA2 and DDX24

Data Source:
BioGRID (two hybrid)

		GLRA2	DDX24
Description		glycine receptor alpha 2	DEAD-box helicase 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glycinergic Synapse	Nucleolus Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Chloride Channel Activity Glycine Binding Extracellularly Glycine-gated Chloride Channel Activity Glycine-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Metal Ion Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Response To Amino Acid Nervous System Process Synaptic Transmission, Glycinergic Excitatory Postsynaptic Potential Cellular Response To Amino Acid Stimulus Cellular Response To Zinc Ion Cellular Response To Ethanol Chloride Transmembrane Transport	RNA Metabolic Process
Pathways		Neurotransmitter receptors and postsynaptic signal transmission Neurotransmitter receptors and postsynaptic signal transmission
Drugs		Glycine Lindane Picrotoxin Ethanol Memantine Taurine
Diseases
GWAS			Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		5 interacting genes: BAG6 DDX24 GDI2 PSD SEC23A	34 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3
Entrez ID		2742	57062
HPRD ID		02379	05860
Ensembl ID		ENSG00000101958	ENSG00000089737
Uniprot IDs		P23416	Q9GZR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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