DESI1 and NT5C3A

Data Source:
BioGRID (two hybrid)

		DESI1	NT5C3A
Description		desumoylating isopeptidase 1	5'-nucleotidase, cytosolic IIIA
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GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity	Nucleotide Binding TRNA 2'-phosphotransferase Activity Magnesium Ion Binding Protein Binding 5'-nucleotidase Activity
	Biological Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal	Pyrimidine Nucleoside Metabolic Process Nucleotide Metabolic Process Dephosphorylation Pyrimidine Nucleoside Catabolic Process Defense Response To Virus
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Drugs
Diseases			Anemia due to disorders of nucleotide metabolism, including: Adenylate kinase (AK) deficiency; Uridine 5-prime monophosphate hydrolase (UMPH1) deficiency
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Estimated glomerular filtration rate ( 31152163) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252)
Interacting Genes		33 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLN2 UBQLNL UHRF2 XPO1 ZBTB46	6 interacting genes: DESI1 GNAQ NDUFAB1 UBQLN1 UBQLN2 VANGL1
Entrez ID		27351	51251
HPRD ID		18590	05871
Ensembl ID		ENSG00000100418	ENSG00000122643
Uniprot IDs		Q6ICB0	A0A024RA81 A0A090N7U2 Q9H0P0
PDB IDs		3EBQ	2CN1 2JGA 2VKQ
Enriched GO Terms of Interacting Partners?
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