SIGLEC9 and SFTPC

Data Source:
BioGRID (two hybrid)

		SIGLEC9	SFTPC
Description		sialic acid binding Ig like lectin 9	surfactant protein C
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Neutrophil Degranulation Regulation Of Immune Response	Respiratory Gaseous Exchange By Respiratory System Cellular Protein Metabolic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation	Surfactant metabolism Defective pro-SFTPC causes SMDP2 and RDS Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Blood protein levels ( 29875488 28240269) Body mass index ( 29273807) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neurological blood protein biomarker levels ( 31320639)	Coronary artery disease ( 29212778) Hypertriglyceridemia ( 23505323)
Interacting Genes		4 interacting genes: BRICD5 LGALS3BP NCS1 SFTPC	36 interacting genes: BSCL2 CD200R1 CD79A CLDN5 CPLX4 CREB3 CXCL9 FAM209A FNDC9 GJA8 GOLM1 GPR152 GPX8 HPN ICAM3 IFNGR2 KLRC1 LMNA LSMEM2 MUC1 NEDD4 PDZK1IP1 PQBP1 PVR SEC22A SEC61G SIGLEC9 SMIM3 SYNE4 TMEM106C TMEM139 TMEM30B TMEM79 TMPRSS2 WWP1 WWP2
Entrez ID		27180	6440
HPRD ID		16133	01520
Ensembl ID		ENSG00000129450	ENSG00000168484
Uniprot IDs		Q9Y336	A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs			2YAD
Enriched GO Terms of Interacting Partners?
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