SIGLEC9 and NCS1

Data Source:
BioGRID (two hybrid)

		SIGLEC9	NCS1
Description		sialic acid binding Ig like lectin 9	neuronal calcium sensor 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Secretory Granule Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Cell Adhesion Cell Surface Receptor Signaling Pathway Neutrophil Degranulation Regulation Of Immune Response	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body mass index ( 29273807) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neurological blood protein biomarker levels ( 31320639)	Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)
Interacting Genes		4 interacting genes: BRICD5 LGALS3BP NCS1 SFTPC	27 interacting genes: C1QTNF2 CDSN CEP89 CREM CTAG1A CTAG1B DRD2 DRD3 DRD5 DTX2 FZD7 GRK2 IL1RAPL1 KCND2 LY6G6D MEOX2 MIEF2 NBL1 OXER1 PI4KB PRDM4 RNASEH1 SFTPA2 SIGLEC9 SPP1 SPRED2 ZC3H10
Entrez ID		27180	23413
HPRD ID		16133	04500
Ensembl ID		ENSG00000129450	ENSG00000107130
Uniprot IDs		Q9Y336	A0A024R8B2 P62166
PDB IDs			1G8I 2LCP 4GUK 5O9S 6QI4
Enriched GO Terms of Interacting Partners?
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