GJB1 and TEX264

Data Source:
BioGRID (two hybrid)

		GJB1	TEX264
Description		gap junction protein beta 1	testis expressed 264, ER-phagy receptor
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane	Autophagosome Membrane Extracellular Region Nucleus Replication Fork Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Platelet Alpha Granule Lumen
	Molecular Function	Gap Junction Channel Activity Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport	Platelet Degranulation Reticulophagy Protein-DNA Covalent Cross-linking Repair
Pathways		Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly	Platelet degranulation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Interacting Genes		57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6	28 interacting genes: ADGRG3 ARL13B CERS4 CLDN2 CLN6 COQ9 CREB3L1 EMP1 FAM209A FFAR2 FFAR3 GABARAPL2 GJB1 GPR152 GPR42 LHFPL4 LHFPL5 MFF MS4A3 NKX3-1 OPRM1 SLC10A2 SLC34A2 SMIM3 TM4SF18 TMEM31 TMEM79 TSPAN12
Entrez ID		2705	51368
HPRD ID		02367	15492
Ensembl ID		ENSG00000169562	ENSG00000164081
Uniprot IDs		A0A654ICJ7 P08034	A0A087WTU3 Q9Y6I9
PDB IDs		1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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