NPTN and SURF2

Data Source:
BioGRID (two hybrid)

		NPTN	SURF2
Description		neuroplastin	surfeit 2
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Plasma Membrane Cell Surface Axon Dendrite Presynaptic Membrane Inhibitory Synapse Schaffer Collateral - CA1 Synapse Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Active Zone Membrane Integral Component Of Postsynaptic Density Membrane	Nucleoplasm Nucleolus Plasma Membrane Nuclear Speck
	Molecular Function	Type 1 Fibroblast Growth Factor Receptor Binding Protein Binding Ion Channel Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity	Molecular_function
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Protein Phosphorylation Cellular Calcium Ion Homeostasis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Cytosolic Calcium Ion Concentration Axon Guidance Visual Learning Positive Regulation Of Neuron Projection Development Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Long-term Synaptic Potentiation Positive Regulation Of ERK1 And ERK2 Cascade Dendrite Self-avoidance Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Receptor Localization To Synapse Positive Regulation Of Cellular Protein Localization Excitatory Synapse Assembly	Biological_process
Pathways		GABA receptor activation
Drugs
Diseases
GWAS		Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Tourette syndrome ( 30818990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Activated partial thromboplastin time ( 22703881) Blood protein levels ( 28240269) Malaria ( 31844061)
Interacting Genes		3 interacting genes: AGTR1 SURF2 UBC	6 interacting genes: APP B4GALT3 NPTN PLAUR PRNP ZNF331
Entrez ID		27020	6835
HPRD ID		18033	15948
Ensembl ID		ENSG00000156642	ENSG00000148291
Uniprot IDs		Q9Y639	Q15527
PDB IDs		6A69
Enriched GO Terms of Interacting Partners?
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