RNF11 and SPRTN

Data Source:
HPRD (two hybrid)

		RNF11	SPRTN
Description		ring finger protein 11	SprT-like N-terminal domain
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Double-stranded DNA Binding Single-stranded DNA Binding Metalloendopeptidase Activity Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Proteolysis Cellular Response To DNA Damage Stimulus Response To UV Protein Autoprocessing Translesion Synthesis Positive Regulation Of Protein Ubiquitination Error-free Translesion Synthesis Protein-DNA Covalent Cross-linking Repair
Pathways			Translesion Synthesis by POLH
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)	Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	3 interacting genes: POLD3 RNF11 UBC
Entrez ID		26994	83932
HPRD ID		09955	13164
Ensembl ID		ENSG00000123091	ENSG00000010072
Uniprot IDs		Q9Y3C5	A0A024R3U2 Q9H040
PDB IDs			5IY4 6MDW 6MDX
Enriched GO Terms of Interacting Partners?
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