RNF11 and ZFYVE16

Data Source:
HPRD (two hybrid)

		RNF11	ZFYVE16
Description		ring finger protein 11	zinc finger FYVE-type containing 16
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome	Early Endosome Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway
Pathways			Signaling by BMP
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)	Blond vs. brown/black hair color ( 30531825) Psoriasis ( 25854761)
Interacting Genes		68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	5 interacting genes: APP EEA1 PPP1CA RNF11 TOM1
Entrez ID		26994	9765
HPRD ID		09955	10319
Ensembl ID		ENSG00000123091	ENSG00000039319
Uniprot IDs		Q9Y3C5	Q7Z3T8
PDB IDs			3T7L 5MK0
Enriched GO Terms of Interacting Partners?
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