GIGYF2 and RBM12

Data Source:
HPRD (two hybrid)

		GIGYF2	RBM12
Description		GRB10 interacting GYF protein 2	RNA binding motif protein 12
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GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding	RNA Binding Protein Binding
	Biological Process	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization	Regulation Of RNA Splicing
Pathways
Drugs
Diseases		Parkinson's disease (PD)
GWAS		Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)	Blood protein levels ( 28240269) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11	5 interacting genes: BRAP GIGYF2 OPTN PRMT2 TBC1D4
Entrez ID		26058	10137
HPRD ID		11639	06212
Ensembl ID		ENSG00000204120	ENSG00000244462
Uniprot IDs		Q6Y7W6	Q9NTZ6
PDB IDs		5NVL 5NVM	1WEL 2CPY 2DNN 2EK1 2EK6
Enriched GO Terms of Interacting Partners?
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