GALT and NQO1

Data Source:
BioGRID (two hybrid)

		GALT	NQO1
Description		galactose-1-phosphate uridylyltransferase	NAD(P)H quinone dehydrogenase 1
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol	Cytoplasm Cytosol Dendrite Neuronal Cell Body Synapse
	Molecular Function	Protein Binding UDP-glucose:hexose-1-phosphate Uridylyltransferase Activity Zinc Ion Binding	RNA Binding NAD(P)H Dehydrogenase (quinone) Activity Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Superoxide Dismutase Activity Protein Binding Identical Protein Binding
	Biological Process	UDP-glucose Metabolic Process Galactose Metabolic Process UDP-glucose Catabolic Process Galactose Catabolic Process Galactose Catabolic Process Via UDP-galactose	Response To Ischemia NADH Oxidation Regulation Of Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Synaptic Transmission, Cholinergic Aging Response To Nutrient Response To Toxic Substance Response To Hormone Response To Carbohydrate Response To Amine Removal Of Superoxide Radicals Response To Estradiol Response To Testosterone Response To Drug Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Response To Alkaloid Positive Regulation Of Neuron Apoptotic Process Cell Redox Homeostasis Response To Ethanol Response To Electrical Stimulus Cellular Response To Hydrogen Peroxide NADPH Oxidation Cellular Response To Metal Ion Response To Tetrachloromethane Response To L-glutamine Response To Hydrogen Sulfide Response To Flavonoid
Pathways		Defective GALT can cause Galactosemia Galactose catabolism	Regulation of ornithine decarboxylase (ODC)
Drugs			Menadione Dicoumarol Duroquinone 3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol ES-936 Cibacron Blue Flavin adenine dinucleotide 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione RH-1 Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE Cannabidiol
Diseases		Galactosemia
GWAS			Alcohol consumption (drinks per week) ( 30679032) Blood osmolality (transformed sodium) ( 28360221) Blood protein levels ( 30072576 29875488) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body mass index ( 26426971) Estimated glomerular filtration rate ( 31015462) Mean platelet volume ( 32888494) Medication use (HMG CoA reductase inhibitors) ( 31015401) Risk-taking tendency (4-domain principal component model) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		7 interacting genes: GRPEL1 KRTAP6-2 NQO1 TNK2 TRIP13 UBTD2 VAC14	9 interacting genes: CDC42 DNAJB1 GALT HIF1A HSPA1A ING1 STUB1 TP53 UBE2D1
Entrez ID		2592	1728
HPRD ID		06106	00518
Ensembl ID		ENSG00000213930	ENSG00000181019
Uniprot IDs		A0A0S2Z3Y7 B2RAT6 P07902	B4DLR8 P15559
PDB IDs		1R3A 5IN3 6GQD	1D4A 1DXO 1GG5 1H66 1H69 1KBO 1KBQ 1QBG 2F1O 3JSX 4CET 4CF6 5A4K 5EA2 5EAI 5FUQ 6FY4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?