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NQO1
Description
NAD(P)H quinone dehydrogenase 1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Dendrite
Neuronal Cell Body
Synapse
Molecular Function
RNA Binding
NAD(P)H Dehydrogenase (quinone) Activity
Cytochrome-b5 Reductase Activity, Acting On NAD(P)H
Superoxide Dismutase Activity
Protein Binding
Identical Protein Binding
Biological Process
Response To Ischemia
NADH Oxidation
Regulation Of Cellular Amino Acid Metabolic Process
Xenobiotic Metabolic Process
Nitric Oxide Biosynthetic Process
Response To Oxidative Stress
Synaptic Transmission, Cholinergic
Aging
Response To Nutrient
Response To Toxic Substance
Response To Hormone
Response To Carbohydrate
Response To Amine
Removal Of Superoxide Radicals
Response To Estradiol
Response To Testosterone
Response To Drug
Negative Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Response To Alkaloid
Positive Regulation Of Neuron Apoptotic Process
Cell Redox Homeostasis
Response To Ethanol
Response To Electrical Stimulus
Cellular Response To Hydrogen Peroxide
NADPH Oxidation
Cellular Response To Metal Ion
Response To Tetrachloromethane
Response To L-glutamine
Response To Hydrogen Sulfide
Response To Flavonoid
Pathways
Regulation of ornithine decarboxylase (ODC)
Drugs
Menadione
Dicoumarol
Duroquinone
3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol
ES-936
Cibacron Blue
Flavin adenine dinucleotide
5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione
RH-1
Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]
3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE
Cannabidiol
Diseases
GWAS
Alcohol consumption (drinks per week) (
30679032
)
Blood osmolality (transformed sodium) (
28360221
)
Blood protein levels (
30072576
29875488
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body mass index (
26426971
)
Estimated glomerular filtration rate (
31015462
)
Mean platelet volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Triglyceride levels (
32203549
)
Novel Interacting Genes
2 novel interacting genes:
CDH16
CDH5
Interacting Genes
9 interacting genes:
CDC42
DNAJB1
GALT
HIF1A
HSPA1A
ING1
STUB1
TP53
UBE2D1
Entrez ID
1728
HPRD ID
00518
Ensembl ID
ENSG00000181019
Uniprot IDs
B4DLR8
P15559
PDB IDs
1D4A
1DXO
1GG5
1H66
1H69
1KBO
1KBQ
1QBG
2F1O
3JSX
4CET
4CF6
5A4K
5EA2
5EAI
5FUQ
6FY4
Enriched GO Terms of Interacting Partners
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