GAST and CPE

Data Source:
HPRD (in vivo)

		GAST	CPE
Description		gastrin	carboxypeptidase E
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Insulin processing
Drugs		Oxetacaine	Insulin human Insulin pork
Diseases
GWAS			Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A
Entrez ID		2520	1363
HPRD ID		00671	00272
Ensembl ID		ENSG00000184502	ENSG00000109472
Uniprot IDs		A0A0E3VY36 P01350	A0A384N679 P16870
PDB IDs		5WRJ
Enriched GO Terms of Interacting Partners?
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