GAST and CP

Data Source:
HPRD (in vitro)

		GAST	CP
Description		gastrin	ceruloplasmin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Lumen Plasma Membrane Extracellular Exosome Blood Microparticle
	Molecular Function	Hormone Activity Protein Binding	Ferroxidase Activity Copper Ion Binding Oxidoreductase Activity Chaperone Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Copper Ion Transport Iron Ion Transport Cellular Iron Ion Homeostasis Post-translational Protein Modification Cellular Protein Metabolic Process Iron Ion Homeostasis
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Metal ion SLC transporters Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) Defective CP causes aceruloplasminemia (ACERULOP) Post-translational protein phosphorylation Iron uptake and transport
Drugs		Oxetacaine	Calcium Iron Zinc Silver Zinc acetate Ferrous gluconate Ferrous succinate Ferrous ascorbate Ferrous fumarate Ferrous glycine sulfate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS			Subcutaneous adipose tissue ( 22589738)
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	7 interacting genes: ATP7A BTRC GAST LTF MPO PLG PROC
Entrez ID		2520	1356
HPRD ID		00671	00317
Ensembl ID		ENSG00000184502	ENSG00000047457
Uniprot IDs		A0A0E3VY36 P01350	A5PL27 P00450
PDB IDs		5WRJ	1KCW 2J5W 4EJX 4ENZ
Enriched GO Terms of Interacting Partners?
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