FKBP8 and TMEM254

Data Source:
BioGRID (two hybrid)

		FKBP8	TMEM254
Description		FKBP prolyl isomerase 8	transmembrane protein 254
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex	Integral Component Of Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding	Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Regulation Of Gene Expression Viral Process Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		48 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1	41 interacting genes: AQP6 ARL13B ATP6V0E1 BCL2L13 BIK CD74 CD79A CERS4 CPLX4 EBP ELOVL4 FAM209A FKBP8 FNDC9 GPR152 GPX8 IFNGR2 IL3RA LEUTX LHFPL5 MFF MMGT1 MTIF3 PAGE1 PLP1 REEP4 RETREG3 SAR1A SEC11C SLC16A2 STOM STX1A SYT1 TMED8 TMEM14B TMEM237 TMEM31 TMEM45B TMEM51 TMEM79 TMX2
Entrez ID		23770	80195
HPRD ID		05327	08501
Ensembl ID		ENSG00000105701	ENSG00000133678
Uniprot IDs		A0A024R7P2 B2R8G6 Q14318	A0A087WZM8 B4DU43 Q8TBM7
PDB IDs		2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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