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HEY1 and FOXH1
Data Source:
BioGRID
(two hybrid)
HEY1
FOXH1
Description
hes related family bHLH transcription factor with YRPW motif 1
forkhead box H1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Activin Responsive Factor Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
BHLH Transcription Factor Binding
Sequence-specific DNA Binding
SMAD Binding
Androgen Receptor Binding
Co-SMAD Binding
R-SMAD Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Pulmonary Valve Morphogenesis
Atrioventricular Valve Formation
Endocardial Cushion Morphogenesis
Cardiac Ventricle Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Notch Signaling Pathway
Anterior/posterior Pattern Specification
Positive Regulation Of Gene Expression
Dorsal Aorta Morphogenesis
Umbilical Cord Morphogenesis
Negative Regulation Of Neuron Differentiation
Negative Regulation Of Notch Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Neurogenesis
Cardiac Epithelial To Mesenchymal Transition
Heart Trabecula Formation
Cardiac Septum Morphogenesis
Ventricular Septum Morphogenesis
Labyrinthine Layer Blood Vessel Development
Arterial Endothelial Cell Differentiation
Notch Signaling Involved In Heart Development
Negative Regulation Of Biomineral Tissue Development
Cellular Response To Glucocorticoid Stimulus
Circulatory System Development
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation
Regulation Of Vasculogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Heart Looping
Secondary Heart Field Specification
Outflow Tract Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Embryonic Heart Tube Anterior/posterior Pattern Specification
Aorta Morphogenesis
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Axial Mesoderm Development
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To Cytokine Stimulus
Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Pathways
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
RUNX2 regulates osteoblast differentiation
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Signaling by NODAL
Signaling by Activin
Drugs
Diseases
GWAS
Blood metabolite levels (
26401656
)
Educational attainment (
25201988
)
General cognitive ability (
29844566
)
Interacting Genes
22 interacting genes:
ARNT
CREBZF
DAZAP2
FBXW7
FOXH1
GATA1
HES1
HEY2
KRTAP6-2
LAPTM5
MDM2
MYOD1
NTRK3
PITX2
PLEKHB2
PRKD2
SKIL
SMAD3
SMAD9
TENT5D
TP53
YTHDF1
67 interacting genes:
AOC1
ARID5A
ATP23
ATXN1L
BATF2
C10orf55
C11orf1
C19orf54
CEACAM6
CRX
CRYBA1
CYSRT1
DAZAP2
DRAP1
FAM168B
FAM83A
FOXD2
FOXG1
HDHD3
HEY1
HLX
HOXA1
HSF4
KLHL26
KRTAP11-1
KRTAP13-3
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP3-1
KRTAP3-3
KRTAP7-1
LASP1
MAGED1
MGAT5B
MSX2
NKX2-5
NOTO
OXER1
PLA2G10
PNMA5
PPP1R37
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR22
RBM46
RBPMS2
RNF144B
SERGEF
SMAD2
SMAD3
SMAD4
SOX14
SOX4
TEKT5
TFG
TLX3
TSC1
UBAP2
UFSP1
ZC3H10
ZIC1
ZNF34
ZNF503
Entrez ID
23462
8928
HPRD ID
04260
04689
Ensembl ID
ENSG00000164683
ENSG00000160973
Uniprot IDs
B4DEI9
Q9Y5J3
O75593
PDB IDs
2DB7
5XOC
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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