ALDOC and SQLE

Data Source:
BioGRID (two hybrid)

		ALDOC	SQLE
Description		aldolase, fructose-bisphosphate C	squalene epoxidase
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding	Squalene Monooxygenase Activity Protein Binding FAD Binding
	Biological Process	Fructose Metabolic Process Gluconeogenesis Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Neutrophil Degranulation Canonical Glycolysis	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cholesterol Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Regulation Of Cell Population Proliferation Regulation Of Cholesterol Biosynthetic Process Lipid Droplet Formation
Pathways		Neutrophil degranulation Glycolysis Gluconeogenesis	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			Naftifine Terbinafine Butenafine Ellagic acid
Diseases
GWAS			Amyotrophic lateral sclerosis ( 24931836) Amyotrophic lateral sclerosis or frontotemporal dementia ( 24931836) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: ANKS1A ATP6V1E1 ERBB2 LNX1 MAP2K3 PLD2 SQLE	6 interacting genes: ALDOC CREB3 CREB3L1 REEP4 TMEM14B ZNF641
Entrez ID		230	6713
HPRD ID		02386	11802
Ensembl ID		ENSG00000109107	ENSG00000104549
Uniprot IDs		A0A024QZ64 P09972	Q14534 Q5HYI4
PDB IDs		1XFB	6C6N 6C6P 6C6R
Enriched GO Terms of Interacting Partners?
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