SQLE

Description		squalene epoxidase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Squalene Monooxygenase Activity Protein Binding FAD Binding
	Biological Process	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cholesterol Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Regulation Of Cell Population Proliferation Regulation Of Cholesterol Biosynthetic Process Lipid Droplet Formation
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		Naftifine Terbinafine Butenafine Ellagic acid
Diseases
GWAS		Amyotrophic lateral sclerosis ( 24931836) Amyotrophic lateral sclerosis or frontotemporal dementia ( 24931836) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ALDOC CREB3 CREB3L1 REEP4 TMEM14B ZNF641
Entrez ID		6713
HPRD ID		11802
Ensembl ID		ENSG00000104549
Uniprot IDs		Q14534 Q5HYI4
PDB IDs		6C6N 6C6P 6C6R
Enriched GO Terms of Interacting Partners?
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