PAXIP1 and ZBTB8A

Data Source:
BioGRID (two hybrid)

		PAXIP1	ZBTB8A
Description		PAX interacting protein 1	zinc finger and BTB domain containing 8A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Matrix Histone Methyltransferase Complex MLL3/4 Complex	Cellular_component Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Histone H3-K36 Methylation Vasculogenesis Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Response To Ionizing Radiation DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Histone Acetylation Negative Regulation Of DNA-binding Transcription Factor Activity Endothelial Cell Migration Positive Regulation Of Isotype Switching Positive Regulation Of Isotype Switching To IgG Isotypes Histone H3-K4 Methylation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Adipose Tissue Development Chorion Development Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Response To DNA Damage Stimulus	Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Bladder cancer (smoking interaction) ( 24662972) Metabolite levels ( 23823483)
Interacting Genes		91 interacting genes: A2M APP ATP1B1 ATP1B3 BTBD16 BTBD6 C2orf42 CABYR CATSPERG CBX8 CCNDBP1 CIAO2B CLU COMTD1 CYB5R4 DCP1A DIS3L DNAJA1 DNAJB11 DYNC2H1 ECSIT EIF3I EIF5B EP300 EPB41L3 FAHD1 FBLN5 FUCA1 H2AX H3C1 HNRNPLL HSPA14 HSPA4L INTS7 LACTB MAPRE2 MAST1 MRPL33 MT-ND1 MT2A MTIF3 MTNR1A NOS3 NPC2 NUPR1 NXT1 PAGR1 PAX2 PCBP2 PCYT1B PGGHG PGM1 PIAS1 PIAS2 PKP4 PLCD1 PML POM121 PPHLN1 PPIA PPP2R5C PRDX6 PSMA6 RNF32 RPA1 RPL12 RPS20 RPS27A SCAMP5 SCCPDH SELENOV SH3GL2 SMAD2 SNX3 SOX30 SPAG4 SPATA18 SUGT1 SUZ12 TCN2 TECR TM2D3 TMEM120A TP53BP1 TRAPPC8 UMPS WDR48 XAGE1B ZBTB8A ZNF251 ZNF280B	76 interacting genes: ACOT12 AEN AP1M1 AP2M1 ARMC7 ARMCX1 BAZ2B BLK BYSL CBX8 CCDC33 CDC37 CDKL3 CEP70 CSNK1D CWF19L2 DDX6 DVL2 DVL3 EHHADH EIF1AD EP300 FAM161A FAM90A1 FXR2 GPATCH2L HIC2 JRK KAT5 KAT7 KIF5B KIF9 KIFC3 LGALS14 LMO3 LNX1 MCM10 MFAP1 MRPL11 MYO15B NTAQ1 PAXIP1 PIAS2 PRKAA2 PRPF3 PRR34 PSMC1 RAD23A RPL9 SDCBP SYT6 TCEA2 TNIP3 TRIM41 UBE2I YES1 ZBTB17 ZBTB24 ZBTB48 ZBTB49 ZCCHC10 ZGPAT ZMAT2 ZNF138 ZNF250 ZNF276 ZNF329 ZNF35 ZNF408 ZNF417 ZNF438 ZNF497 ZNF572 ZNF587 ZNF648 ZNF837
Entrez ID		22976	653121
HPRD ID		08491	18902
Ensembl ID		ENSG00000157212	ENSG00000160062
Uniprot IDs		Q6ZW49	D3DPQ1 Q96BR9
PDB IDs		3SQD
Enriched GO Terms of Interacting Partners?
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