PAXIP1 and CCNDBP1

Data Source:
BioGRID (two hybrid)

		PAXIP1	CCNDBP1
Description		PAX interacting protein 1	cyclin D1 binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Matrix Histone Methyltransferase Complex MLL3/4 Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Histone H3-K36 Methylation Vasculogenesis Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Response To Ionizing Radiation DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Histone Acetylation Negative Regulation Of DNA-binding Transcription Factor Activity Endothelial Cell Migration Positive Regulation Of Isotype Switching Positive Regulation Of Isotype Switching To IgG Isotypes Histone H3-K4 Methylation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Adipose Tissue Development Chorion Development Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Response To DNA Damage Stimulus	Cell Cycle Regulation Of Cell Cycle
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Bladder cancer (smoking interaction) ( 24662972) Metabolite levels ( 23823483)
Interacting Genes		91 interacting genes: A2M APP ATP1B1 ATP1B3 BTBD16 BTBD6 C2orf42 CABYR CATSPERG CBX8 CCNDBP1 CIAO2B CLU COMTD1 CYB5R4 DCP1A DIS3L DNAJA1 DNAJB11 DYNC2H1 ECSIT EIF3I EIF5B EP300 EPB41L3 FAHD1 FBLN5 FUCA1 H2AX H3C1 HNRNPLL HSPA14 HSPA4L INTS7 LACTB MAPRE2 MAST1 MRPL33 MT-ND1 MT2A MTIF3 MTNR1A NOS3 NPC2 NUPR1 NXT1 PAGR1 PAX2 PCBP2 PCYT1B PGGHG PGM1 PIAS1 PIAS2 PKP4 PLCD1 PML POM121 PPHLN1 PPIA PPP2R5C PRDX6 PSMA6 RNF32 RPA1 RPL12 RPS20 RPS27A SCAMP5 SCCPDH SELENOV SH3GL2 SMAD2 SNX3 SOX30 SPAG4 SPATA18 SUGT1 SUZ12 TCN2 TECR TM2D3 TMEM120A TP53BP1 TRAPPC8 UMPS WDR48 XAGE1B ZBTB8A ZNF251 ZNF280B	115 interacting genes: ADGRA2 AMPD2 AQP1 ARHGAP22 ATP4B C22orf23 C6orf226 CCDC146 CCDC187 CCND1 CDK18 CDKN2A CFAP65 CNNM3 CUL5 DMRT3 DOCK2 FAM110A FAM126A FAM161A FAM74A4 FH FZD10 GAS2L2 GLIDR GRAP2 GSTK1 HBZ HDAC4 HMGB1 HSPB1 ILF2 IMP3 IRGC LIN37 LNX1 MAP2K2 MOS MRPL15 MRPS9 MTDH NAIF1 NANOS2 NEURL3 NOL7 NSMF NUDCD3 PAXIP1 PIAS2 PIMREG PLEKHA7 PMP2 POLDIP3 POLL PRPF31 PSMB10 PTF1A RARA RARB RBP5 RPL28 RPL39L RPL7L1 RPLP0 RPS28 SASH1 SHFL SIRT6 SLC16A13 SPG7 STK25 SYF2 TCEAL1 TEAD4 TFPT THAP10 THAP7 TMEM120B TRAPPC5 TTC23 TYMSOS WNT11 ZBTB24 ZGPAT ZNF124 ZNF136 ZNF155 ZNF169 ZNF20 ZNF223 ZNF230 ZNF334 ZNF394 ZNF417 ZNF439 ZNF440 ZNF480 ZNF490 ZNF552 ZNF555 ZNF557 ZNF564 ZNF578 ZNF581 ZNF627 ZNF670 ZNF696 ZNF697 ZNF707 ZNF785 ZNF786 ZNF835 ZNF837 ZNRF2P1 ZSCAN26
Entrez ID		22976	23582
HPRD ID		08491	06156
Ensembl ID		ENSG00000157212	ENSG00000166946
Uniprot IDs		Q6ZW49	O95273
PDB IDs		3SQD	3AY5
Enriched GO Terms of Interacting Partners?
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