SCMH1 and TOB1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCMH1	TOB1
Description		Scm polycomb group protein homolog 1	transducer of ERBB2, 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromocenter	Nucleus Cytoplasm CCR4-NOT Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Transcription Corepressor Activity Protein Binding Receptor Tyrosine Kinase Binding SMAD Binding
	Biological Process	Chromatin Remodeling Spermatogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Drugs		Mercaptoethanol
Diseases
GWAS		Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737 29892015) General risk tolerance (MTAG) ( 30643258) Height ( 20881960 25282103 23563607 18391952) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435)	Blood protein levels ( 28240269)
Interacting Genes		19 interacting genes: EWSR1 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M SFMBT1 SFMBT2 TMEM11 TOB1 UBQLN1 UBQLN4	19 interacting genes: APP CDC7 CNOT7 CORO7 DTL ERBB2 MAPK1 MAPK9 MARCKS PABPC1 SCMH1 SETDB1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD9
Entrez ID		22955	10140
HPRD ID		11540	09273
Ensembl ID		ENSG00000010803	ENSG00000141232
Uniprot IDs		B3KMZ7 Q96GD3	P50616
PDB IDs		2P0K	2D5R 2Z15 5CI8 5CI9
Enriched GO Terms of Interacting Partners?
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