ZNF510 and MLH3

Data Source:
BioGRID (two hybrid)

		ZNF510	MLH3
Description		zinc finger protein 510	mutL homolog 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Synaptonemal Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Chiasma Mismatch Repair Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding	Chromatin Binding Satellite DNA Binding Protein Binding ATP Binding ATPase Activity Centromeric DNA Binding Mismatched DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Female Meiosis I Protein Localization
Pathways		Generic Transcription Pathway	Meiotic recombination
Drugs
Diseases			Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
GWAS			Inflammatory bowel disease ( 23128233) Mood instability ( 29187730) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: APC AURKA BRAF BUB1 CCND1 CDH1 CTNNA1 DLC1 EGFR FBXW7 MLH3 MSH2 ODC1 PDGFRL PTPN12 PTPRJ SMAD1 SMAD2 SMAD4 STK11 TGFBR2	45 interacting genes: AKT1 ALDOB ANP32B AOPEP AR BAAT CCDC180 CDC14B CDK8 CTSV CYLC2 DVL1 FANCC FBP1 FBP2 FRAT2 GALNT12 HEMGN HRAS HSD17B3 IGFBP3 LEF1 MAP2K1 MLH1 MSANTD3 MSH4 NANS PPP2CB PPP3R2 RASA1 SEC61B SFRP2 SMAD1 STX17 TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRIM55 TRIM63 TSTD2 XPA ZDHHC17 ZNF510
Entrez ID		22869	27030
HPRD ID		18348	05094
Ensembl ID		ENSG00000081386	ENSG00000119684
Uniprot IDs		Q6NUI8 Q9Y2H8	Q2M1Z1 Q9UHC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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