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ZNF510 and PTPN12
Data Source:
BioGRID
(two hybrid)
ZNF510
PTPN12
Description
zinc finger protein 510
protein tyrosine phosphatase non-receptor type 12
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Podosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Focal Adhesion
Cell Projection
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Metal Ion Binding
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Non-membrane Spanning Protein Tyrosine Phosphatase Activity
Protein Binding
SH3 Domain Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Protein Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
ERBB2 Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tissue Regeneration
Cellular Response To Cytokine Stimulus
Cellular Response To Epidermal Growth Factor Stimulus
Negative Regulation Of ERBB Signaling Pathway
Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways
Generic Transcription Pathway
SHC1 events in ERBB2 signaling
SHC1 events in ERBB2 signaling
EGFR downregulation
Signaling by PDGF
Downregulation of ERBB2 signaling
Interleukin-37 signaling
Constitutive Signaling by Overexpressed ERBB2
Drugs
Tiludronic acid
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Estimated glomerular filtration rate (
31015462
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Interacting Genes
21 interacting genes:
APC
AURKA
BRAF
BUB1
CCND1
CDH1
CTNNA1
DLC1
EGFR
FBXW7
MLH3
MSH2
ODC1
PDGFRL
PTPN12
PTPRJ
SMAD1
SMAD2
SMAD4
STK11
TGFBR2
57 interacting genes:
AATK
ABL1
ANP32B
APP
BAG6
BCAR1
CCDC180
CGA
CSH1
CSH2
CSK
EFS
EGFR
ERBB3
ERBB4
FANCC
FGFR2
FGFR4
FLT3
FRAT2
GRB2
IFT20
IGF1R
INSR
JAK2
KDR
LMTK2
LPXN
MYCBP2
NEDD9
PPP3R2
PRKACA
PRKCA
PSG9
PSTPIP1
PSTPIP2
PTK2
PTK2B
PTK7
PXN
RBM19
ROR2
SFRP4
SHC1
SMAD1
SMAD5
SORBS2
STX16
STX17
TENM1
TEX10
TGFB1I1
THAP2
UTRN
WAS
ZFP2
ZNF510
Entrez ID
22869
5782
HPRD ID
18348
02513
Ensembl ID
ENSG00000081386
ENSG00000127947
Uniprot IDs
Q6NUI8
Q9Y2H8
B4E105
Q05209
PDB IDs
5HDE
5J8R
5O2P
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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