FKBP2 and RAP2A

Data Source:
BioGRID (two hybrid)

		FKBP2	RAP2A
Description		FKBP prolyl isomerase 2	RAP2A, member of RAS oncogene family
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Crohn's disease ( 28067908) Fruit consumption ( 32066663)	Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		14 interacting genes: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN2 UBQLN4 VAMP2	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		2286	5911
HPRD ID		01742	01547
Ensembl ID		ENSG00000173486	ENSG00000125249
Uniprot IDs		P26885 Q53XJ5	P10114
PDB IDs		2PBC 4NNR	1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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