SCAF8 and TEX11

Data Source:
BioGRID (two hybrid)

		SCAF8	TEX11
Description		SR-related CTD associated factor 8	testis expressed 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage Factor Complex Nuclear Matrix	Synaptonemal Complex Central Element Chromosome
	Molecular Function	RNA Polymerase II Complex Binding RNA Binding MRNA Binding Protein Binding RNA Polymerase Core Enzyme Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding	Protein Binding
	Biological Process	Termination Of RNA Polymerase II Transcription MRNA Polyadenylation Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Bisphosphonate-associated atypical femoral fracture ( 31006051) Colorectal or endometrial cancer ( 26621817) Diabetic kidney disease ( 26305897) Estimated glomerular filtration rate ( 31152163) Lipoprotein (a) levels ( 26377243)	Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		3 interacting genes: GIGYF1 GOLGA2 TEX11	91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414
Entrez ID		22828	56159
HPRD ID		11487	02256
Ensembl ID		ENSG00000213079	ENSG00000120498
Uniprot IDs		A0A0A0MT33 B7Z3A4 B7Z876 Q9UPN6	Q8IYF3
PDB IDs		2DIW 3D9I 3D9J 3D9K 3D9L 3D9M 3D9N 3D9O 3D9P
Enriched GO Terms of Interacting Partners?
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