FGF8 and PTX3

Data Source:
BioGRID (pull down)

		FGF8	PTX3
Description		fibroblast growth factor 8	pentraxin 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm External Side Of Plasma Membrane	Extracellular Region Extracellular Space Extracellular Matrix Specific Granule Lumen Tertiary Granule Lumen
	Molecular Function	Fibroblast Growth Factor Receptor Binding Type 1 Fibroblast Growth Factor Receptor Binding Type 2 Fibroblast Growth Factor Receptor Binding Growth Factor Activity Chemoattractant Activity	Complement Component C1q Complex Binding (1->3)-beta-D-glucan Binding Protein Binding Identical Protein Binding Virion Binding
	Biological Process	MAPK Cascade Branching Involved In Blood Vessel Morphogenesis Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Organ Induction Mesonephros Development Neural Plate Morphogenesis Positive Regulation Of Protein Phosphorylation Heart Looping Blood Vessel Remodeling Heart Morphogenesis Outflow Tract Septum Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Response To Oxidative Stress Gastrulation Motor Neuron Axon Guidance Mesodermal Cell Migration Positive Regulation Of Cell Population Proliferation Gonad Development Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Animal Organ Morphogenesis Dorsal/ventral Pattern Formation Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Pallium Development Subpallium Development Forebrain Dorsal/ventral Pattern Formation Cell Proliferation In Forebrain Forebrain Neuron Development Signal Transduction Involved In Regulation Of Gene Expression Cell Differentiation Neuron Differentiation Regulation Of Cell Migration Male Genitalia Development Thyroid Gland Development Otic Vesicle Formation Midbrain-hindbrain Boundary Development Dorsal/ventral Axon Guidance Embryonic Heart Tube Development Limb Morphogenesis Embryonic Hindlimb Morphogenesis Aorta Morphogenesis Odontogenesis Regulation Of Odontogenesis Of Dentin-containing Tooth Response To Drug Negative Regulation Of Neuron Apoptotic Process Cell Fate Commitment Positive Regulation Of Cell Differentiation Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Organ Growth Embryonic Neurocranium Morphogenesis Forebrain Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Cardiac Muscle Tissue Development Pharyngeal System Development Corticotropin Hormone Secreting Cell Differentiation Thyroid-stimulating Hormone-secreting Cell Differentiation Bone Development Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Neuroepithelial Cell Differentiation Positive Regulation Of ERK1 And ERK2 Cascade Dopaminergic Neuron Differentiation Cell Migration Involved In Mesendoderm Migration Larynx Morphogenesis	Ovarian Cumulus Expansion Response To Yeast Inflammatory Response Opsonization Extracellular Matrix Organization Neutrophil Degranulation Negative Regulation By Host Of Viral Process Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Phagocytosis Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Glycoprotein Metabolic Process
Pathways			Neutrophil degranulation
Drugs
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Systolic blood pressure ( 30578418)	Body mass index ( 26426971)
Interacting Genes		5 interacting genes: FGFR1 FGFR2 FGFR3 FGFR4 PTX3	15 interacting genes: C1QA C1QB C1QC CFH FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF22 FGF5 FGF7 FGF8 MTNR1A
Entrez ID		2253	5806
HPRD ID		02727	03928
Ensembl ID		ENSG00000107831	ENSG00000163661
Uniprot IDs		A0A087X1S5 A1A515 P55075	P26022
PDB IDs		2FDB
Enriched GO Terms of Interacting Partners?
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