MS4A2 and TMEM86A

Data Source:
BioGRID (two hybrid)

		MS4A2	TMEM86A
Description		membrane spanning 4-domains A2	transmembrane protein 86A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Fc-epsilon Receptor I Complex	Integral Component Of Membrane
	Molecular Function	Protein Binding IgE Binding	Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity
	Biological Process	Inflammatory Response Immune Response Fc-epsilon Receptor Signaling Pathway
Pathways		Fc epsilon receptor (FCERI) signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization FCERI mediated NF-kB activation
Drugs		Omalizumab
Diseases		Asthma
GWAS		Alzheimer's disease ( 31473137)	Ovarian reserve ( 22116950)
Interacting Genes		11 interacting genes: AKT1 APP FCER1A GRB2 HSP90AA1 LYN PRKCD PTPN11 PTPN6 SYK TMEM86A	47 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35C2 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP
Entrez ID		2206	144110
HPRD ID		00915	08292
Ensembl ID		ENSG00000149534	ENSG00000151117
Uniprot IDs		A0A0B4J2E9 Q01362	Q8N2M4
PDB IDs
Enriched GO Terms of Interacting Partners?
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