TMEM86A and GPR37L1

Data Source:
BioGRID (two hybrid)

		TMEM86A	GPR37L1
Description		transmembrane protein 86A	G protein-coupled receptor 37 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane
	Molecular Function	Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding
	Biological Process		Negative Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Ovarian reserve ( 22116950)	Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)
Interacting Genes		47 interacting genes: AQP2 AQP3 BCL2L13 CD79A CISD2 CNR2 COQ9 CPLX4 CREB3L1 EBP ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 FXYD3 GJB4 GJB5 GJC1 GORAB GPR37L1 HAVCR2 KASH5 KCNA1 LHFPL5 LMNA MS4A2 MUC1 NCAPH2 PDZK1IP1 PGRMC2 PI16 REEP4 RIC3 RNF185 SCN3B SLC10A6 SLC18A1 SLC30A2 SLC35C2 SLC39A2 SSMEM1 THAP4 TIMMDC1 TMEM31 TMPRSS2 TYROBP	52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B
Entrez ID		144110	9283
HPRD ID		08292	13603
Ensembl ID		ENSG00000151117	ENSG00000170075
Uniprot IDs		Q8N2M4	O60883
PDB IDs
Enriched GO Terms of Interacting Partners?
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