SKA1 and SKA2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, two hybrid)

		SKA1	SKA2
Description		spindle and kinetochore associated complex subunit 1	spindle and kinetochore associated complex subunit 2
Image
GO Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Microtubule Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)	Cognitive function ( 25644384) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239)
Interacting Genes		13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1	6 interacting genes: HMOX2 IFT57 PRKD3 RALY SKA1 SPC24
Entrez ID		220134	348235
HPRD ID		12689	13306
Ensembl ID		ENSG00000154839	ENSG00000182628
Uniprot IDs		A0A024R294 Q96BD8	J3KSP0 Q8WVK7
PDB IDs		4AJ5 4C9Y 4CA0	4AJ5
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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