SKA1 and SSC5D

Data Source:
BioGRID (two hybrid)

		SKA1	SSC5D
Description		spindle and kinetochore associated complex subunit 1	scavenger receptor cysteine rich family member with 5 domains
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton Mitotic Spindle	Extracellular Space Cytoplasm Membrane Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Microtubule Binding	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Regulation Of Microtubule Polymerization Or Depolymerization Cell Division	Endocytosis Defense Response Multicellular Organism Development Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Large HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		13 interacting genes: AURKB BLOC1S6 CCDC196 CCDC197 FAM9C NDC80 PSMC5 SKA2 SKA3 SNAPIN SPC24 SSC5D SYCE1	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		220134	284297
HPRD ID		12689	11444
Ensembl ID		ENSG00000154839	ENSG00000179954
Uniprot IDs		A0A024R294 Q96BD8	A1L4H1
PDB IDs		4AJ5 4C9Y 4CA0
Enriched GO Terms of Interacting Partners?
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