MTIF3 and THBD

Data Source:
BioGRID (two hybrid)

		MTIF3	THBD
Description		mitochondrial translational initiation factor 3	thrombomodulin
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GO Annotations	Cellular Component	Mitochondrion	Extracellular Space Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Apicolateral Plasma Membrane
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Signaling Receptor Activity
	Biological Process	Ribosome Disassembly Mitochondrial Translational Initiation	Female Pregnancy Blood Coagulation Response To X-ray Negative Regulation Of Platelet Activation Negative Regulation Of Blood Coagulation Response To Lipopolysaccharide Leukocyte Migration Response To CAMP Negative Regulation Of Fibrinolysis
Pathways		Mitochondrial translation initiation	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs			Drotrecogin alfa Ibuprofen Dexibuprofen
Diseases			Inherited thrombophilia
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)	Blood protein levels in cardiovascular risk ( 28369058) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Venous thromboembolism ( 26888256)
Interacting Genes		84 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202	31 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC19A3 SLC35C2 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID		219402	7056
HPRD ID		17609	01764
Ensembl ID		ENSG00000122033	ENSG00000178726
Uniprot IDs		Q9H2K0	P07204
PDB IDs		6NEQ 6NF8 6RW4 6RW5	1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3
Enriched GO Terms of Interacting Partners?
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