KHDRBS2 and CATSPER1

Data Source:
BioGRID (two hybrid)

		KHDRBS2	CATSPER1
Description		KH RNA binding domain containing, signal transduction associated 2	cation channel sperm associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Plasma Membrane Motile Cilium CatSper Complex
	Molecular Function	MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding	Calcium Activated Cation Channel Activity Voltage-gated Calcium Channel Activity Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Calcium Ion Transport Multicellular Organism Development Spermatogenesis Cell Differentiation Flagellated Sperm Motility Response To Progesterone Regulation Of Ion Transmembrane Transport Sperm-egg Recognition Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Calcium Ion Transmembrane Transport
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Sperm Motility And Taxes
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340)
Interacting Genes		47 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPK HNRNPLL KHDRBS3 LINC01018 LMNTD2 LNX1 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBM10 RBM14 RBM3 RBMX RFC3 SDCBP SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837	116 interacting genes: ABLIM3 ADAMTSL4 AGR2 AGR3 AJUBA AKAP8L APOA2 ARID5A BEGAIN C11orf1 C11orf16 C9orf24 CARD10 CDPF1 CHIC2 CHRD CPSF7 CTBP2 CYSRT1 EFEMP2 EMD EYA2 FHL5 FRS3 FST GLI1 HNRNPH1 HOXA1 IKZF3 KHDRBS2 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LASP1 LCE1D LCE1E LCE1F LCE2C LIMS1 LZTS2 MDFI MTUS2 MYCL NBPF19 NOTCH2NLA PAK5 PDLIM7 PLA2G10 PLAGL2 PLSCR1 PLSCR3 PMF1-BGLAP PPP1R32 PTPN21 RFX6 RGS19 RGS20 RIMBP3 RSPO2 SCRG1 SIVA1 SORBS3 SPRY2 SPRY3 SSC4D TGFB1 TNS2 TRAF2 TRIM27 TRIM42 TRIM8 TRIP6 TSPAN4 VWC2 ZBTB42 ZIM2 ZNF688 ZNF774 ZNF837
Entrez ID		202559	117144
HPRD ID		13775	09396
Ensembl ID		ENSG00000112232	ENSG00000175294
Uniprot IDs		A0A6Q8PGH5 Q5VWX1	Q8NEC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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