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ELK4 and MAPK11
Data Source:
HPRD
(in vitro)
ELK4
MAPK11
Description
ETS transcription factor ELK4
mitogen-activated protein kinase 11
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Protein Serine/threonine Kinase Activity
MAP Kinase Activity
Protein Binding
ATP Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Histone H3 Deacetylation
Activation Of MAPK Activity
Protein Phosphorylation
Ras Protein Signal Transduction
Positive Regulation Of Gene Expression
Positive Regulation Of Interleukin-12 Production
Intracellular Signal Transduction
Positive Regulation Of Erythrocyte Differentiation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Muscle Cell Differentiation
Stress-activated MAPK Cascade
Negative Regulation Of Cardiac Muscle Cell Proliferation
Cellular Response To Interleukin-1
Cellular Response To Virus
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
NOD1/2 Signaling Pathway
p38MAPK events
p38MAPK events
ERK/MAPK targets
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Oxidative Stress Induced Senescence
DSCAM interactions
VEGFA-VEGFR2 Pathway
activated TAK1 mediates p38 MAPK activation
Activation of the AP-1 family of transcription factors
KSRP (KHSRP) binds and destabilizes mRNA
Myogenesis
Myogenesis
RHO GTPases Activate NADPH Oxidases
Regulation of TP53 Activity through Phosphorylation
Drugs
Minocycline
KC706
Regorafenib
Diseases
Prostate cancer
GWAS
Acne (severe) (
24927181
)
Adult body size (
32376654
)
Interacting Genes
11 interacting genes:
BRCA1
FOS
ID1
ID2
ID3
MAPK1
MAPK11
MAPK3
MAPK7
MAPK8
SRF
27 interacting genes:
APP
ATF2
BCL2
C9orf78
CCND1
CPNE6
DUSP10
DUSP16
EEF2K
ELK1
ELK4
ESR2
HDAC3
HTRA2
JUN
MAPKAPK5
MAPT
MBP
NOXA1
PML
POLR3D
PPM1D
RPS6KA5
SH2D1A
SOCS3
TAB1
ZNHIT1
Entrez ID
2005
5600
HPRD ID
02592
04208
Ensembl ID
ENSG00000158711
ENSG00000185386
Uniprot IDs
A0A024R985
A0A024R997
P28324
Q8IXL1
Q15759
PDB IDs
1BC7
1BC8
1HBX
1K6O
3GC8
3GC9
3GP0
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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