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EEF1A1 and AQP2
Data Source:
BioGRID
(two hybrid)
EEF1A1
AQP2
Description
eukaryotic translation elongation factor 1 alpha 1
aquaporin 2
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Transport Vesicle Membrane
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Lumenal Side Of Membrane
Molecular Function
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
Calmodulin Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
Water Transmembrane Transporter Activity
Protein Binding
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Biological Process
Translation
Translational Elongation
Neutrophil Degranulation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
Renal Water Homeostasis
Renal Water Transport
Water Transport
Glycerol Transport
Cellular Response To Water Deprivation
Protein Homotetramerization
Transmembrane Transport
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Metanephric Collecting Duct Development
Pathways
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
Congenital nephrogenic diabetes insipidus (NDI)
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
)
Obsessive-compulsive disorder (
22889921
)
Interacting Genes
130 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCDC130
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CSRP2
DARS1
DIABLO
DLEU1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RBBP8
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSPY1
TSPYL2
TTLL12
TTR
UBQLN4
WARS1
XPO5
XRN2
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
60 interacting genes:
ACTB
BCAP31
C4orf3
CCDC167
CDIPT
CERT1
CLCA4
CLDN7
CREB3
CREB3L1
CTSA
CXCL16
EEF1A1
EFNA5
ELL2
ERG28
ERGIC3
ERMP1
FAM209A
GPAA1
GPX8
IER3
IGFBP5
INSIG2
LEUTX
LHFPL5
MRM1
MS4A13
MUC1
NDFIP2
OLFM4
OR10AG1
PANX1
PDZK1IP1
PLP2
PNLIPRP1
RTP2
SLC26A6
SLC30A2
SLC38A7
SLC5A2
SNAP47
SNX5
SPCS1
SSR3
STUB1
STX8
SUPT20H
TM9SF2
TMEM109
TMEM218
TMEM230
TMEM236
TMEM60
TMEM86A
TMEM97
TRARG1
UBE2J1
VAPB
YIPF6
Entrez ID
1915
359
HPRD ID
00559
00141
Ensembl ID
ENSG00000156508
ENSG00000167580
Uniprot IDs
P68104
Q6IPS9
P41181
PDB IDs
1SYW
3C5J
6ZMO
4NEF
4OJ2
6QF5
Enriched GO Terms of Interacting Partners
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